Table of Contents Overview In the search for safer, longer-lasting solutions to arthritis pain, many natural approaches to joint health maintenance have been explored.\u00a0 Glucosamine Sulfate, Chondroitin Sulfate and MSM have long been at the forefront of Maximum Joint Health Benefits. Now, reports from the latest research with glucosamine and chondroitin are confirming the added value of using these and other joint nutrients in optimal combinations. Drugs used to treat arthritis are designed to relieve symptoms, but not to reverse the underlying causes of the pain.\u00a0 These arthritis\u00a0drugs\u00a0may work for a while, but most of them have been linked to dangerous side effects.\u00a0\u00a0 In fact, researchers have found that many common arthritis drugs actually\u00a0speed up\u00a0the progression of arthritis! Choose Pain Relief That Heals and Maximum Joint Health Benefits Joint cartilage must constantly repair and rebuild itself in order to function properly as a \u201ccushion.\u201d\u00a0 One of the main building blocks needed for making and maintaining joint cartilage is\u00a0glucosamine.\u00a0 The two major forms of glucosamine sold as supplements are\u00a0glucosamine sulfate\u00a0and\u00a0glucosamine hydrochloride. Why Glucosamine Sulfate Is Superior to Other Forms Glucosamine stimulates the manufacture of key structural components of cartilage (called\u00a0glycosaminoglycans), but it is also necessary for the absorption of sulfur into the cartilage.\u00a0The presence of sulfur in glucosamine sulfate appears to be the reason that it has consistently outperformed glucosamine hydrochloride in joint health research. Used by millions of people worldwide, glucosamine sulfate has been the subject of more than 300 scientific investigations, and more than 20 double-blind studies. One of the key reasons why glucosamine sulfate is so effective is its small molecular size.\u00a0 The smaller molecular structure allows it to penetrate the joint cartilage quickly. Glucosamine can then be delivered more rapidly to the cartilage cells, providing joints with lubrication and shock absorption. Glucosamine and Chondroitin Enhance Each Other Chondroitin\u00a0is also a major component of joint cartilage produced by the body.\u00a0 Chondroitin serves to help absorb fluid into the cartilage, block harmful enzymes from breaking it down, and aid in production of new cartilage. Chondroitin sulfate actually consists of repeating units of glucosamine.\u00a0 A chondroitin sulfate molecule is, therefore, 50-300 times larger than glucosamine sulfate. Although glucosamine sulfate is superior to chondroitin sulfate ineffectiveness, research has shown that both products work better when taken in combination. MSM Reduces Arthritis Pain Moreover, the MSM\u00a0(methyl sulfonyl methane) is a sulfur-containing compound that helps support joints, tendons, and muscles. MSM is often referred to as organic sulfur, or \u201cjoint sulfur.\u201d\u00a0 Sulfur is the fourth most abundant mineral in our bodies, and medical studies over the years have found that arthritic joints have lower than normal sulfur levels. In one important study, the sulfur concentration in arthritic cartilage was discovered to be only about one-third the level of normal cartilage. MSM helps provide Maximum Joint Health Benefits with the abundant supply of sulfur needed for proper functioning and repair.\u00a0 Researchers at the UCLA School of Medicine conducted a double-blind study and found that patients taking MSM experienced an average 82 percent improvement in arthritis pain. In comparison, patients taking the placebo reported no more than a 20 percent improvement.\u00a0 The study\u2019s author concluded that \u201cMSM may offer a significant new nutritional substance for the control of arthritic pain as a safe, non-toxic method.\u201d How Vitamin C and Manganese Maximum Joint Health Benefits Vitamin C is essential for the building of collagen, cartilage, and joint tissue. It also has other important Maximum Joint Health Benefits. As an antioxidant, Vitamin C neutralizes unstable molecules called free radicals that damage and destroy cells. Free radicals are found in joint fluids of people with inflamed joints.\u00a0 Studies have shown Vitamin C also suppresses the release of certain proteins that promote inflammation such as occurs in arthritis. Manganese is an important mineral, vital to the formation of cartilage, collagen, and connective tissue. Without manganese, the production of cartilage grinds to a stop, even in the presence of substantial levels of glucosamine. Studies have shown that when added to joint supplements including glucosamine and chondroitin, manganese brought about additional improvements in arthritic patients. This important mineral seems to enhance the effectiveness of other joint supplements. Research indicates that the human body\u2019s ability to utilize manganese declines with age. In addition, deficiencies of manganese have long been recognized in the veterinary community as a cause of joint and other musculoskeletal problems in animals. These findings point to a connection between declining manganese levels in aging cartilage and the development of osteoarthritis in the elderly. symptoms, but not to reverse the underlying causes of the pain.\u00a0 These arthritis drugs may work for a while, but most of them have been linked to dangerous side effects. In fact, researchers have found that many common arthritis drugs actually speed up\u00a0the progression of arthritis!